期刊文献+

广东地区人群牙周炎与冠心病的血清学研究 被引量:4

下载PDF
导出
摘要 目的:比较广东地区不同人群中血清炎症因子和牙周指标的差异,为牙周炎与冠心病相关性研究提供一定的实验依据。方法:对44例伴有冠心病的牙周炎患者,48例慢性牙周炎患者和45名健康志愿者血清超敏C反应蛋白(hs-CRP)水平进行检测,并对伴有冠心病的牙周炎患者以及慢性牙周炎患者进行牙周检查,记录牙周临床指标(包括牙周袋深度,附着丧失以及探诊出血指数)。结果:伴有冠心病的牙周炎组hs-CRP显著高于慢性牙周炎组和健康对照组(P<0.05),慢性牙周炎组的hs-CRP水平又显著高于健康对照组(P<0.05)。伴有冠心病的牙周炎组的牙周探诊深度、附着丧失水平和龈沟出血指数高于慢性牙周炎组(P<0.05)。结论:牙周炎可以引起hs-CRP水平升高,冠心病可能会加重牙周炎水平。
出处 《实用医学杂志》 CAS 北大核心 2012年第16期2751-2753,共3页 The Journal of Practical Medicine
基金 广东省自然科学基金项目(编号:9151026003000003) 广州市科技计划项目(编号:11C26040763)
  • 相关文献

参考文献17

  • 1Libby P, Okamoto Y, R.ocha V Z, et al. Inflammation in atherosclerosis: transition from theory to practice [J]. Circ J, 2010,74(2) : 213-220.
  • 2孟焕新.牙刷病学[M].3版.北京:人民卫生出版社,2008:75-91.
  • 3欧阳翔英.牙周疾病与冠状动脉性心脏病的关系[J].北京大学学报(医学版),2008,40(1):112-115. 被引量:36
  • 4Ford P J, Yamazaki K, Seymour G J. Cardiovascular and oral disease interactions: what is the evidence[J].? Prim Dent Care, 2007,14(2) :59-66.
  • 5Linda L. Humphrey, Rongwei Fu, et al. Periodontal disease and coronary heart disease incidence: a systematic review and meta-analysis [J]. J Gen Intern Med, 2008,23(12):2079- 2086.
  • 6Ridker P M. C-reactive protein and the prediction of cardiovascular events among those at intermediate risk: moving an inflammatory hypothesis toward consensus [J]. J Am Coll Cardiol, 2007, 49(21): 2129-2138.
  • 7Tousoulis D, Charakida M, Stefanadis C. Endothelial function and inflammation in coronary artery disease [J].Postgrad Med J, 2008,84(993): 368-371.
  • 8Devaraj S, Yun J M, Adamson G, et al. C-reactive protein impairs the endothelial glycocalyx resulting in endothelial dysfunction [J].Cardiovasc Res. 2009. 84 (3), 479-484.
  • 9Con'ado E, Rizzo M, Coppola G, et al. An update on the role of markers of inflammation in atherosclerosis [J].J Atheroscler Thromb, 2010, 17 ( 1 ) : 1-11.
  • 10Forner L, Larsen T, Kilian M, et al. Incidence of bacteremia after chewing, tooth brushing and scaling in individuals with periodontal inflammation [J]. J Clin Periodontol, 2006, 33 (6) : 401-407.

二级参考文献78

  • 1黄琪,胡申江.血链球菌感染与冠心病关系的研究进展[J].国外医学(内科学分册),2004,31(11):466-469. 被引量:1
  • 2占定凤,刘志伟,夏肖萍,胡建成,陈莉丽,严杰.16S rDNA多重PCR检测牙周组织感染菌及混合感染与慢性牙周炎病变程度关系的研究[J].中华流行病学杂志,2005,26(2):120-123. 被引量:6
  • 3刘平,王苏加,张运,张成河,郑培惠.冠心病患者的牙周病患病率较高[J].中国动脉硬化杂志,2005,13(1):36-36. 被引量:4
  • 4Meurman JH, Sanz M, Janket SJ. Oral health, atherosclerosis, and cardiovascular disease [J]. Crit Rev Oral Biol Med, 2004, 15 (6): 403-13.
  • 5Spahr A, Klein E, Khuseyinova N, et al. Periodontal infections and coronary heart disease: role of periodontal bacteria and importance of total pathogen burden in the coronary event and periodontal disease (CORODONT) study [J ]. Arch Intern Med, 2006, 166 (5): 554-9.
  • 6Arbes SJ Jr, Slade GD, Beck JD. Association between extent of periodontal attachment loss and self-reported history of heart attack: an analysis of NHANES III data [J]. J Dent Res, 1999,78 (12): 1777-82.
  • 7Briggs JE, McKeown PP, Crawford VL, et al. Angiographically confirmed coronary heart disease and periodontal disease in middle-aged males[J]. J Periodontol, 2006, 77(1): 95-102.
  • 8Lopez R, Oyarzun M, Naranjo C, et al. Coronary heart disease and periodontitis --a case control study in Chilean adults [J]. J Clin Periodontol, 2002, 29(5): 468-73.
  • 9Meurman JH, Janket S J, Qvamstrom M, et al. Dental infections and serum inflammatory markers in patients with and without severe heart disease [J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2003, 96(6): 695-700.
  • 10Zaremba M, Gorska R, Suwalski P, et al. Evaluation of the incidence of periodontitis-associated bacteria in the atherosclerotic plaque of coronary blood vessels [J ]. J Periodontol, 2007, 78(2): 322-7.

共引文献41

同被引文献26

引证文献4

二级引证文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部