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活化的蛋白激酶C受体1(RACK1 Receptor for Activated C Kinase1)在肿瘤相关方面的研究进展 被引量:1

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摘要 RACK1是G蛋白β亚基的同族体,是一种胞浆内游离的支架蛋白,它可以通过不同的WD40位点,结合、转运PKC到细胞内相应的位置,并使其保持活性状态。近期一些研究证实,RACK1除可与细胞膜上活化的PKC结合发生反应外,还可结合多种胞浆蛋白或亚细胞结构,参与多条代谢通路,发挥不同的生理作用。
机构地区 中国医科大学
出处 《中国医学工程》 2012年第5期179-179,181,共2页 China Medical Engineering
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参考文献8

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同被引文献10

  • 1White C D,Brown M D,Sacks D B.IQGAPs in cancer:a family of scaffold proteins underlying tumorigenesis [ J ].FEBS Lett 2009,583(12):1817-24.
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