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A Novel Protocol for the Regioselective Bromination of Primary Alcohols in Unprotected Carbohydrates or Glycosides

A Novel Protocol for the Regioselective Bromination of Primary Alcohols in Unprotected Carbohydrates or Glycosides
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摘要 The regioselective and efficient bromination of primary hydroxyl groups in unprotected carbohydrates or glycosides is successfully achieved by using (chloro-phenylthio-methylene)dimethylammoniumchloride (CPMA) in the presence of tetrabutylammonium bromide (TBAB) in dry DMF. The regioselective and efficient bromination of primary hydroxyl groups in unprotected carbohydrates or glycosides is successfully achieved by using (chloro-phenylthio-methylene)dimethylammoniumchloride (CPMA) in the presence of tetrabutylammonium bromide (TBAB) in dry DMF.
出处 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2012年第7期1429-1432,共4页 中国化学(英文版)
基金 Supporting information for this article is available on the WWW under http://dx.doi.org/10.1002/cjoc.201200211 or from the author.Acknowledgement The work was financially supported by the Fundamental Research Funds for the Lanzhou University (lzujbky-2011-136) and the Natural Science Foundation for Young Scientists in Gansu Province, China (Grant No. 1 107RJYA038).
关键词 REGIOSELECTIVE BROMIDE CPMA free sugars GLYCOSIDES regioselective, bromide, CPMA, free sugars, glycosides
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