摘要
Chemical examination of a Chinese gorgonian Anthogorgia sp. resulted in the isolation of seven terpenoids, including two new compounds, an rearranged serrulatane-type diterpenoid anthogorgiene P （1） and a guaiazuenebased terpenoid anthogorgiene Q （2）. Anthogorgiene P （1） contains an unprecedented cubebane nucleus which is rarely found from nature. The structures of new compounds were elucidated on the basis of extensive spectroscopic methods （IR, UV, MS, CD and NMR）. Compound 7 showed potent antifouling activity against the larval settlement of Balanus amphitrite, while 1 and 4 possessed moderate inhibition.
Chemical examination of a Chinese gorgonian Anthogorgia sp. resulted in the isolation of seven terpenoids, including two new compounds, an rearranged serrulatane-type diterpenoid anthogorgiene P （1） and a guaiazuenebased terpenoid anthogorgiene Q （2）. Anthogorgiene P （1） contains an unprecedented cubebane nucleus which is rarely found from nature. The structures of new compounds were elucidated on the basis of extensive spectroscopic methods （IR, UV, MS, CD and NMR）. Compound 7 showed potent antifouling activity against the larval settlement of Balanus amphitrite, while 1 and 4 possessed moderate inhibition.
