骨髓活检在血小板减少诊断中的价值

Diagnostic value of bone marrow biopsy in thrombocytopenia

目的探讨骨髓活检和骨髓涂片在血小板减少诊断中的意义。方法回顾性分析157例血小板减少患者骨髓涂片和骨髓活检切片的临床资料,分别观察骨髓涂片和活检切片的增生程度、骨髓造血容积、巨核细胞数及阳性结果检出率。结果骨髓组织切片能准确地反映骨髓细胞增生程度,阳性结果检出率高于骨髓涂片。结论骨髓活检可作为血小板减少重要的鉴别诊断依据,骨髓活检和涂片同步观察能有效提高血液病诊断率,减少误诊率。

Objective To investigate the significance of bone marrow biopsy （BMB） and smears in the diagnosis of thrombocytopcnia. Method Clinical data of 157 cases of patients with thrombocytopenia were retrospectively an- alyzed about bone marrow smears and BMB slices, with thc hyperplasia of bone marrow smears and biopsy slices, haematogenesis volume of bone marrow, the number of mcgakaryocyte and positiverdetcction ratio respectively ex- amined. Results Bone marrow slices can accurately present the hyperplasia of bone marrow cells. Positive detec- tion rate is higher than that of bonc marrow smears. Conclusions Bone marrow biopsy can be considcrcd as an im- portant diagnosis evidence for differentiating thrombocytopenia. The application of synchronous observation of bone marrow and slices can effectively help improve the diagnostic rate of blood disease, reducing the misdiagnosis rate.