主动免疫治疗不明原因复发性自然流产的临床分析

Clinical analysis of the active immunotherapy in unexplained recurrent spontaneous abortion

目的探讨主动免疫治疗不明原因复发性自然流产的临床疗效及对分娩结局的效果。方法选择2010年1月～2012年1月期间在我院就诊的不明原因复发性自然流产患者30例为观察组,并给予淋巴细胞注射及常规保胎药物治疗;选择同期在我院就诊的不明原因复发性自然流产患者33例为对照组,并在妊娠后给予常规保胎药物治疗。结果观察组妊娠成功率为90%,而对照组则为54.55%,两组相比较差异有显著性意义(P<0.01),观察组随访27例中并未出现并发症、低体重儿、畸形儿,观察组在新生儿Apgar评分与同期分娩组相比较差异无统计学意义(P>0.05)。结论主动免疫治疗不明原因复发性自然流产是一种无风险、无毒副作用、费用低、治愈率高的理想治疗方法。

Objective To investigate the clinical efficacy and effects on birth outcomes of the active immunotherapy in unexplained recurrent spontaneous abortion. Methods 30 patients with unexplained recurrent spontaneous abortion in the observation group were chosen from January 2010 to January 2012 in our hospital, and were given the lymphocyte injection and conventional tocolytic drug to be treated. And 33 patients with unexplained recurrent spontaneous abortion for the control group were chosen at the same period in our hospital, were given the conventional tocolytic drug to be treated treatment in pregnancy. Results The pregnancy success rate of the observation group was 90%, and the control group was 54.55% , the difference of two groups was significant （P 〈0.01）, there were no complica- tions, low birth weight children and deformed children in 27 cases which were followed up in the obser- vation group, there were no statistically significant between two groups of Apgar score （P 〉 0.05）. Con- clusions The active immunotherapy in unexplained recurrent spontaneous abortion is a risk--free, non-- toxic side effects, low cost, high cure rate and ideal treatment way.