翼状胬肉角膜缘干细胞移植术与单纯切除术的比较

The comparison between limbus stem cell transplantation and simple excision of pterygium

目的比较单纯翼状胬肉切除与干细胞移植术治疗翼状胬肉的临床效果。方法 196例(255眼)翼状胬肉采用单纯胬肉切除术,212例(235眼)翼状胬肉采用自体角膜缘干细胞移植术,分别术后随访6到24月。结果术后复发率:单纯翼状胬肉切除术组为34.9%,自体角膜缘干细胞移植术组为3.4%,复发率两组比较差异有统计学意义(P<0.01)。结论自体角膜缘干细胞移植为病变区提供了新的干细胞来源,治疗较单纯胬肉切除效果好,复发率低.手术简单易行,值得推广。

Objective To compare the clinical efficacy of the simple pterygium excision and ptergium excision combined with autologous limbal stem cell transplantation . Methods 196 cases （ 255 eyes） received the simple pterygium excision, 212 eases （235 eyes） received ptergium excision combined with autologous limbal stem cell transplantation .All eases were followed up 6 to 24 Months. Results Postoperative recurrence rates： simple pterygium excision of group was 34.9%, Autologous corneal limbal stem cell transplantation unit was 3.4%. Recurrence rate between two groups was statistically different （P〈0.01）. Conclusion Autologous corneal limbal stein cell transplantation provided a new source of stem cells. It has better effect of treatment and lower recurrence rate. This surgery method is easy to operate, and worth being extended.