异位妊娠患者的甲氨喋呤保守治疗与手术治疗效果对比

The Effect of Contrast of the Methotrexate Conservative Treatment and Surgical Treatment of Ectopic Pregnancy

目的对比应用甲氨喋呤与开腹手术、腹腔镜手术对异位妊娠的治疗效果。方法输卵管妊娠患者180例,根据治疗方法分为甲氨喋呤组、开腹手术组及腹腔镜组各60例,对比三组疗效。结果 MTX组住院天数显著高于其他两组(P<0.01);腹腔镜组输卵管通畅率显著高于其他两组(P<0.01);腹腔镜组术中出血量、手术时间及术后排气时间均显著短于开腹组(P<0.01)。结论 MTX疗效确切,腹腔镜手术治疗EP显著优于其他两种方法,MTX及腹腔镜治疗难以凑效时,开腹手术仍需考虑。

Objective To contrast the clinical effects of Methotrexate（MTX）, laparotomy, and laparoscopic surgery in patients with ectopic pregnancy（EP）. Methods 180 patients with EP were randomly devided into three groups（n=60）, MTX group, laparotomy group, and laparoscopic surgery group, the clinical effects were contrasted between the three groups. Results The length of stay in MTX group was significantly longer than the other two groups（P〈0.01）, tubal patency rate in laparoscopic surgery group was significantly higher（P〈0.01）, and the intraoperative blood loss, operative time, postoperative passage of flatus in laparoscopic surgery group were significantly lower than laparotomy group（P〈0.01）. Conclusion MTX has exact efficacy in treatment of EP, and laparoscopic surgical is significantly better than the other two methods, When MTX and laparoscopic treatment can not achieve the desired results, open surgery needs to be taken into account.