比索洛尔联合阿司匹林治疗高血压合并大脑中动脉狭窄的临床观察

Bisoprolol in Combination with Aspirin Treatment of Hypertension and Cerebral Artery Stenosis Observed

目的探究比索洛尔联合阿司匹林用来治疗高血压并发大脑中动脉狭窄的治疗的方法和治疗效果。方法选取60例高血压合并大脑中动脉狭窄的患者,随机分为治疗组和对照组,在治疗6个月后,进行TCD检查和血小板聚集率的测定,然后比较患者用药前后大脑中动脉收缩峰值流速(Vp)值的变化情况,以及血小板聚集率的变化情况,整理分析临床疗效。结果治疗组的用药有效率为97%,高于对照组的73%,说明治疗组的药物治疗有效,效果优于对照组;并且治疗组大脑中动脉收缩峰值流速(Vp)值和血小板聚集率改善情况均优于对照组,两组结果比较,差异有统计学意义(P<0.01)。结论比索洛尔对控制血压,改善脑血流,预防脑血栓疗效显著。

Objective Bisoprolol treatment of hypertension and the efficacy ofmiddle cerebral artery stenosis and treatment of cerebralhemodynamics. Methods Sixty patients with hypertension and middle cerebral artery stenosis were randomly divided into bisoprolol （Kangxin） and nifedipine （control group）, 6 months after the review of TCD and platelet aggregation, comparison before and after treatment contraction of the middle cerebral artery peak velocity （Vp） value changes, platelet aggregation and clinical efficacy. Results The clinical efficiency of 97%, 73% of the control group, treatment group than the control group; treatment group contraction of the middle cerebral artery peak velocity （Vp） to improve the value and platelet aggregation than the control group, the difference was statistically significant （P〈0.01）. Conclusion Bisoprolol for the control of blood pressure, improving cerebral blood flow, prevention of cerebral significant effect.