微电极记录技术在帕金森病手术中的应用

Application of microelectrode recording in operation for Parkinson's disease

目的 应用微电极记录技术提高帕金森病手术的靶点定位精度。方法 在苍白球毁损术 (1 4例 )、丘脑毁损术 (8例 )病人中 ,采用微电极电生理记录技术进行术中靶点监测。结果 最终毁损靶点较MR更换率为81 8% ,手术效果优良 ,有效率 1 0 0 % ,无永久并发症。结论 应用微电极技术能显著提高靶点定位精度 。

Objective: To increase the precision of target localization in Parkinson's disease surgery. Methods: Microelectrode recording was used in intraoperactive target localization in patients undergone pallidotomy (14 cases), thalamotomy (8 cases). Results: The final targets had been greatly changed compared with MR targets, and the change rate was about 81 8%. The effect of surgery was so excellent that every patient showed improvement, and no patient showed permanent complication. Conclusions: Microelectrode recording can highly increase the preciseness of target localization , decrease the rate of complication and produce a better outcome.