摘要
目的 :为探讨宫颈癌患者放疗后的细胞免疫功能情况。方法 :应用抗人 T淋巴细胞单克隆抗体 OKT系统对 6 6例宫颈癌放疗后患者外周血 T淋巴细胞亚群进行检测 ,并将复发组与无复发组的检测结果进行比较分析。结果 :宫颈癌放疗后患者 OKT3,OKT4及 OKT4/OKT8值均降低 ,其中复发组比无复发组降低更为明显 (P <0 .0 1)。结论 :宫颈癌患者放疗后细胞免疫功能下降 ;复发患者细胞免疫功能下降更为显著。
Objective:In order to know the result of cellular immunity in patients with cervix carcinoma after radiotherapy Methods:Anti human T Lymphocyte monoclonal antibody technique was used to determine the T Lymphocyte subsets of peripheral blood in the 66 patients with cervix carcinoma after radiotherapy The results of determination in 21 recurrent patients and 45 no recurrent patients were compared and analyzed Results:The percentage of OKT 3、OKT 4and the ratio of OKT 4/OKT 8 were lower in the patients after radiotherapy,in the recurrent group it was much lower than that in the no recurrent group(P<0 01) Conclusion:The cellular immunity in the patients with cervix carcinoma after radiotherapy decreased to the lower level,and it decreased more significantly in the recurrent patients
出处
《广西医学》
CAS
2000年第4期683-684,共2页
Guangxi Medical Journal
关键词
宫颈癌
细胞免疫功能
放射疗法
Cervix carcinoma
Cellular immunity
Recurrence
T Lymphocyte