不同剂量尿激酶静脉溶栓治疗急性脑梗塞疗效比较

Comparison of differential doses of urokinase in patients with acute cerebral infarction

目的 :观察不同剂量尿激酶在溶栓治疗中的作用。方法 :应用尿激酶 (U K) 15 0万 u组与 5 0万 u× 3天组静脉溶栓治疗发病 2 4小时内的急性脑梗塞各 15例。结果 :UK15 0万 u组总有效率 5 3.3% ,与对照组相比差别无显著性 ;U K5 0万 u× 3天组总有效率 80 % ,与对照组相比差别有显著性。并发脑出血发生率 U K15 0万 u组 13.3% ,UK5 0万 u× 3天组6 .7%。结论 :认为 UK5 0万 u× 3天组对于病程 2 4小时内的急性脑梗塞有较好疗效。

Objective:30 patients(15 in each group) with acute cerebral infarction(ACI) onset within 24h were treated by urokinase(UK) 150u and 50u for days respectively Results:Total effective rate in 150u group was 53 3% There was no significant difference between the two groups Total effective rate in the group of 50u for 3 days was 80% It showed a significant difference with the controlled group Complication of cerebral hemorrhage incidence in former group was 13 3% and in the latter was 6 7% We thought that patients with ACI in 24h in the latter had a better result than the former