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羟脯氨酸衍生的双功能催化剂的合成与应用 被引量：3

Synthesis and Application of Bifunctional Catalysts Derived from Hydroxyproline
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摘要 以(L)羟脯氨酸为初始原料,设计合成了分别含有硫脲、磺酰胺和方酰胺等官能团的三类有机小分子催化剂,并将其用于醛与N-Boc亚胺的不对称anti-Mannich反应,分别比较了它们的催化活性. Three kinds of chiral bifunctional organoeatalysts, containing thiourea, sulfonylamide and squaramides functionalities, respectively, were designed and synthesized with 4 hydroxyproline as the start material. A preliminary study was made of their activity in catalyzing the asymmetric anti-Mannich reaction between aldehydes and N-Boc imine.
作者 钏永明 李佳丽 彭云贵
机构地区 中国科学院成都有机化学研究所 西南大学化学化工学院
出处 《西南大学学报（自然科学版）》 CAS CSCD 北大核心 2012年第7期48-52,共5页 Journal of Southwest University(Natural Science Edition)
基金 国家自然科学基金资助项目(20872120)
关键词 有机催化剂 不对称催化 anti-Mannich反应 N-Boc亚胺 organocatalyst asymmetric catalysis anti-Mannich reaction N-Boc imine
分类号 O621.3 [理学—有机化学]
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参考文献10

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共引文献2

同被引文献20

  • 1陈荣,杨晓兰,冯小明.1－［5－（3－甲基苯基）－2H－四唑－2－乙酰基］－4－芳酰基氨基硫脲及其环化反应[J].西南师范大学学报（自然科学版）,1994,19(5):494-498. 被引量：1
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引证文献3

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西南大学学报（自然科学版）
2012年 第7期

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