微柱凝胶技术鉴测孕妇血清IgG抗体水平

Determination of IgG antibody in Pregnant women serum with microcolumn Gel test

目的建立一种新的微柱凝胶技术鉴测孕妇血清中IgG抗体水平。方法采用微柱凝胶抗球蛋白试验测定IgG血型抗体。结果检测299例“O”型孕妇中IgG抗A(B)效价>64占106例(3.5％),观察其中55例,经二次以上鉴测并经中草药防治有41例(74.4％)约3/4IgG抗A(B)效价下降至64以下。结论通过鉴测孕妇血清中IgG抗体水平用中草药防治新生儿溶血病是有效的。

Objective To set up a new method to assay serum IgG of pregnant women with microcoiumnGel test. Methods Microcolumn test was used to determinate the blood group antibody IgG. Results: 106 patients whose serum anti -A (B) IgG liter > 64 were detected in 299 pregnant women with '0' blood group, respectively. In 55 patients (IgG liter > 64) which were assayed more than twice and treated with Chinese traditional herbs, we found the anti - A (B) IgG tiler of 41 palients had decreased to the levels below 64. Conclusion With the delermination of IgG anlibody using ihe mi-crocolumn Gel test in pregnanl women serum, we found lhat Chinese Iraditional herbs treatmenl have significant effects on preventing exacerbation of hemolytic disease of newborn (HDN) .