水痘病毒血清流行病学研究

Seroepidemiological Survey of Variclla Zoster Virus

用酶联免疫吸附试验检测了 1998年杭州、台州 2地区 136 3名 0～ 6 3岁健康人群血清水痘带状疱疹病毒 (VZV)抗体。结果显示 :VZV抗体总阳性率为 5 8 47% ;男、女阳性率 ,不同地区阳性率 ,2月份、5月份、11月份抗体阳性率均无显著性差异 ;<3个月婴儿阳性率只有 8 33% ;8～ 12岁 ,13～ 2 0岁 ,2 0岁以上阳性率分别为 6 3 45 %、83 2 3%和 92 5 5 %。表明婴儿、幼儿、学前班儿童、小学低年级学生对VZV缺乏免疫力 ,是今后我国接种水痘疫苗 。

To study seroepidemiological aspect of varicella zoster virus(VZV)in healthy plpulation to provide scientific basis,for working out immunity tactics of varicella vaccine and controlling effectively varcella prevalence.1363 health persons of 0 to 63 years in Hang Zhou and Tai Zhou were studied of VZV antibody by ELISA in 1998.The seropsitive rate of VZV antibody was 58\^47%.There were no significant differences in the prevalance of antibody between male and female,in different places and those in February,May,November.The positive rate for infant(<3 months old)was 78\^95%,children(3 months to 7 years old)17\^83% and the positive rate for persons 8 to 12 years,13 to 20 years and more than 20 years were 63\^45%,83\^23%,and 92\^55% respectively.The rate for the children of 3 years old is only 8\^33%.Infant and beinglow school children in immunity level to VZV were the main immunifactioners of varicella vaccine.