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三阴性乳腺癌临床病理学特征分析

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摘要 目的通过回顾性分析三阴性乳腺癌(TNBC)与非三阴性乳腺癌(Non-TNBC)的临床病理学特征的差异,揭示TNBC的生物学特性。方法收集浙江省肿瘤医院乳腺癌病例543例,比较TNBC与Non-TNBC在发病年龄、月经状况、家族史、身高、体质量、肿瘤大小、淋巴结状态、病理分期及病理类型等的差异。结果 TBNC发病年龄为(49±10)岁,Non-TNBC发病年龄为(47±9)岁。TNBC组与Non-TNBC组发病年龄、月经状况、家族史、BMI、病理类型差异无统计学意义(>0.05),肿瘤大小、淋巴结状态及病理分期差异有统计学意义(<0.05)。结论相对于Non-TNBC,TNBC具有肿块更大、淋巴结转移更多、分期更晚等特点,根据其临床病理学特性,规范化、个体化治疗每个TNBC病例,以降低TNBC的复发率、转移率,提高TNBC的3年无进展生存率和总生存率是临床治疗需要关注的重点。
机构地区 浙江省肿瘤医院
出处 《现代实用医学》 2012年第7期801-803,共3页 Modern Practical Medicine
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