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铅的中枢神经毒性机制研究进展 被引量:11

Progress in study on neurotoxic mechanism of lead
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摘要 铅在人体蓄积产生毒性,大脑为其最主要的靶器官之一,铅对发育中的大脑可产生不可逆的神经毒性。本文就近年来铅的神经毒性及其机制的相关研究进行综述,旨在为后续研究提供参考。 Accumulation in human body of lead can produce toxicity, brain especially the developing brain is one of its main target organs. This is a review on lead neurotoxicity and its mechanism, aimed at providing reference for future studies.
出处 《中国工业医学杂志》 CAS 北大核心 2012年第4期274-276,共3页 Chinese Journal of Industrial Medicine
基金 武汉市卫生局公共卫生科研项目(项目编号WGHD05)
关键词 神经毒性 脂质过氧化 细胞凋亡 内质网应激基因 lead neurotoxicity lipid peroxidation apoptosis ER stress gene
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