1MULKEEN A L,SILVA T,YOO P S,et al.Shon interfering RNA mediated gene silencing of vascular endothelial growth factor:Effects on cellular proliferation in colon cancer cells[J].Arch Surg,2006,141(4):367-374.
2HANAHAN D,FOLKM J.Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis[J].Cell,1996,86(3):353-364.
3FOLKLNAN J.Angiogenesis in cancer,vascular,rheumatoid and other disease[J].Nat Med,1995,1(1):27-31.
4DAVID L,MALLET C,MAZERBOURG S,et al.Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells[J].Blood,2007,109(5):1953-1961.
5ZHANG X,DENG H X,ZHAO X,et al.RNA interference mediated silencing of the phosphatidylinositol 3-kinase catalytic subunit attenuates growth of human ovarian cancer cells in vitroand in vivo[J].Oncology,2009,77(1):22-32.
7COHEN M H,GOOTENBERG J,KEEGAN P,et al.FDA drug approval summary:bevacizumab (Avastin) plus carboplatin and paclitaxel as first-line treatment of advanced/metastatic recurrent nonsquamous non-small cell lung cancer[J].Oncologist,2007,12(6):713-718.
8PRESTA L G,CHEN H,O′CONNOR S J,et al.Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders[J].Cancer Res,1997,57(20):4593-4599.
