摘要
用 Wenger 植物神经平衡因子分析法,随机检测75例眩晕证患者的植物神经功能状态;用检测白细胞介素-2受体(IL-2R)活性的方法,随机检测49例眩晕证肝炎患者。结果:眩晕证植物神经功能异常以交感神经功能增强为主;肝炎患者(眩晕证及无眩晕证)IL-2R 活性显著低于健康人(P<0.001),在肝炎患者中伴有眩晕证的 IL-2R 活性低于无眩晕证者(P<0.01);在眩晕证肝炎患者中,IL-2R 活性虚证的低于实证,病程长的低于病程短的(P 均<0.05),而性别及年龄的影响不大。眩晕证多属中医学的风证范畴。为此提示:"风"可能与交感神经功能增强、免疫功能低下或缺陷有关。
The authors used Wenger's vegetative nervous balance factor analysis to measure vegetative nervous function of 75 patients with vertigo revealing enhancement of sympathetic nervous function. The proliferation activity of IL-2 receptor was determined by the amount of ~3H-TdR incorporated cpm in the peripheral blo6d lymphocyte after exogenous IL-2 stimulation(Lymphocult-T).The authors used this technique to measure the activity of IL-2 receptor in 49 patients with hepatitis and vertigo.The results showed that the activity of IL-2 receptor in patients with or without vertigo was lower than the controls(P<0.001).And patients with vertigo showed lower activity of IL-2 receptor than that without(P<0.01).In these patients with asthenia-syndrome the activity of IL-2 receptor was lower than those with sthenia syndrome.The activity of IL-2 receptor in these patients with long course was lower than those with short course.The difference of sex and age was not significant. The above results suggest that'Wind'in TCM might be related to the enhancement of sympathetic nervous function and the activity of IL-2 receptor.
基金
本项研究获中山医科大学及省卫生厅资助
