针刺配合康复训练干预脑卒中后认知障碍疗效观察

Observations on the Efficacy of Acupuncture plus Rehabilitation Training in Treating Post-stroke Cognitive Disorder

目的评价针刺配合康复训练治疗脑卒中后认知障碍的临床疗效。方法将60例具有认知障碍脑卒中患者随机分为针康组和药物组,治疗8星期后,观察治疗前后两组患者在简易智能状态检查表(Mini-Mental State Examination,MMSE)、神经行为认知状态量表(NCSE)及患者血浆皮质醇的变化。结果治疗前后两组患者MMSE评分、NCSE评分、血浆皮质醇含量比较差异均有统计学意义(P<0.05);治疗8星期后,两组MMSE比较差异有统计学意义(P<0.05);针康组的NCSE评分明显高于药物组(P<0.05);针康组血浆皮质醇的含量低于药物组(P<0.05)。结论针刺配合康复训练能够明显地促进脑卒中后认知功能的恢复,降低血浆皮质醇的含量,且疗效优于药物尼莫地平治疗。

Objective To investigate the clinical efficacy of acupuncture plus rehabilitation training in treating post-stroke cognitive disorder. Method Sixty patients with post-stroke cognitive disorder were randomly allocated to acupuncture plus rehabilitation and medication groups. After 8 weeks of treatment, changes in the Mini-Mental State Examination （MMSE） score, the Neurobehavioral Cognitive Status Examination （NCSE） score and plasma hydrocortisone were observed in the two groups of patients Result There were statistically significant pre-/post-treatment differences in the MMSE score, the NCSE score and the plasma content of hydrocortisone in both groups. After 8 weeks of treatment, there was a statistically significant difference in the MMSE score between the two groups （P^0.05）; the MMSE score was significantly higher in the acupuncture plus rehabilitation group than in the medication group （P^0.05）. The plasma content of hydrocortisone was significantly lower in the acupuncture plus rehabilitation group than in the medication group （P〈0.05）. Conclusion Acupuncture plus rehabilitation can significantly promote the post-stroke recovery of cognitive ability and reduce the plasma content of hydrocortisone. Its therapeutic effect is superior to that of nimodipine.