了哥王的化学成分研究

Chemical Constituents of Wikstroemia Indica

目的研究了哥王Wikstroemia indica（L.）C.A.Mey.化学成分。方法运用硅胶、凝胶等多种色谱技术对了哥王的化学成分进行研究,并根据理化性质和波谱数据鉴定化合物结构。结果从了哥王85%乙醇提取物的醋酸乙酯和正丁醇萃取部位分离并鉴定了9个化合物,分别为西瑞香素（daphnoretin）、柚皮素（naringin）、3,5,7-二羟基-4＇-甲氧基二氢黄酮醇（3,5,7-trihydroxy-4′-methoxy-dihydroflavonol）、对羟基苯甲酸（4-hydroxybenzoic acid）、苯甲酸（benzoic-acid）、伞形花内酯（umbdheforne）、daphnogitin、sikokianin B、芫花素（genkwanin）。结论化合物2~5为首次从该植物中分离得到。

OBJECTIVE To study the chemical constitutents from Wikstroemia indica （L.） C. A. Mey. METHODS Silica gel column, Sephadex LH-20 column chromatography were used for separation and purification of the compounds and extensive spectral analysis spectrum were employed for structural elucidation. RESULTS Nine compounds were isolated from EtOAc and n-butanol fraction of the 85% ethanol extract of the W. indica and identified as daphnoretin, naringin, 3,5,7-trihydruxy-4＇-methoxy-dibydroflavonol, 4-hydroxybenzoic acid, benzoic-acid, umbdheforne, daphnogitin, sikokianin B, and genkwanin. CONCLUSION Compounds 2-5 are obtained from the plants of W. indica for the first time.