摘要
应用复方益气养阴汤口服,对41例胆道术后出现气阴两亏患者的胆汁某些生化指标进行观察。在胆色素结石组19例中,10例服药前后与对照组9例相比,总胆红素、游离胆红素、钙离子浓度及β-葡萄糖醛酸苷酶活性明显降低(P<0.05～0.01),而胆汁酸明显升高(P<0.05);胆固醇结石的服药组与对照组各11例相比,上述指标除结合胆红素明显降低(P<0.05)、游离胆红素无明显变化(P>0.05)外,其它指标的变化与胆色素结石组相同。另外,两组胆汁四种成分比值显示游离胆红素和胆固醇下降,胆汁酸增高。说明本方对成石性胆汁成分有较明显的影响。
There were 41 postoperative patients of cholelithiasis with manifestation of Qi-Yin deficiency,had treated with Yiqi Yangyin Prescription.The regimens was 2 weeks as a course, thereafter bile specimens were taken through T tube drainage,and biochemical analysis were performed in order to determine the composition,in consequence of the comparison of the treated patients with the control groups.There were 19 patients of bile pigment stone in whom 10 treated with the prescription and 9 were served as control.The results showed that the total bilirubin, unconjugated bilirubin,the concentration of calcium ion and the activity of β-glucuronidase were markedly decreased as compared to those in the control group(P<0.05),the concentration of bile acid markedly increased than that in the control group(P<0.05).There were 22 patients of cholesterol stone,11 treated with the prescription and 11 were served as control group.The results were the same as in bile pigment stone group except decreased in conjugated bilirubin(P<0.05),and the unconjugated bilirubin were remained unchanged(P>0.05)as compared to the control group. The ratio of unconjugated bilirubin to total bilirubin and the ratio of bile acid to bilirubin were markedly decreased as compared to those in the control group.The above observation showed promptly that Yiqi-Yangyin Prescription gave a promise influence on lithogenic bile of cholelith- iasitic patients,and also investigated the mechanism of the prescription used for deficiency patients with biliary troubles.
