健康体检人群血液流变学参数影响因素的logistic回归分析

Logistic regression analysis on influential factors of hemorheology indicators in physical examination crowd

目的探讨健康体检人群血液流变学参数的影响因素,为预防相关疾病提供理论依据。方法分析北京市2010年健康体检人群资料,收集可能与血液流变学参数相关的指标,进行单因素χ2分析,初步筛选其中有统计学意义的指标,并进一步采用logistic回归模型筛选血液流变学参数的影响因素。结果 5885例健康体检者中血液流变学全血粘度指标3项异常者占5.3%。经单因素分析初步有统计学意义的指标3个,进入logistic回归模型,最终筛选出2个影响因素,分别为性别和年龄。结论血液流变学特性的改变与性别、年龄有密切关系,男性和中、老年人应定期检测血液流变学,有利于疾病的早期发现与防治。

Objective To screen the factors influencing hemorheology indicators of physical examination crowd,so as to provide evidence to prevent related diseases.Methods The data of physical examination crowd of 2010 in Beijing was analyzed.Indicators,which could possibly be related with hemorheology parameters,were collected,screened for statistically significant indicators by using One-Way Crosstabes analysis.Factors influencing hemorheology parameters were further screened by using logistic regression analysis.Results Among 5 885 subjects accepting physical examination,5.3% were with abnormality of three indicators of whole blood viscosity.Three indicators were confirmed to be with statistical significance by One-Way Crosstabes analysis,among which tow indicators,including gender and age.Conclusion Changes of hemorheological characteristics might be closely related with gender and age.Routine hemorheologital detection in man and population of middle and old age could be helpful for early diagnosis and prevention of diseases.