早产儿血细胞参数的统计与分析

Statistical analysis of blood cell parameters in premature infants

目的对不同出生时龄的早产儿血细胞参数进行统计分析,计算其在不同时间的均值和范围,了解早产儿血细胞参数的变化规律。方法收集整理191例早产儿的临床资料,对资料按性别和时龄分组,应用正态分布法和回归分析法等统计学方法进行统计。结果各观测值正态性检验,P>0.05;不同性别的六组早产儿的血细胞参数均值比较差异无统计学意义(P>0.05),并得到不同性别和时龄的平均值和95%CI;组间显著性比较,除RBC无组间差异外(P>0.05),其余参数均有组间差异(P<0.01或P<0.05);与出生后的时间有线性相关的参数有RBC、Hb、HCT、MCV、L%、N%和PLT。结论早产儿血细胞参数与文献报道有一定差距,早产儿出生12h前后细胞参数变化较为明显。

Objective To statistically analyze blood parameters of premature infants at different hours-old,calculate the mean values and ranges at different time points and explore the variation of blood cell parameters.Methods Clinical information of 191 premature infants were collect and sorted,all enrolled infants were divided into different groups according to gender and hours-age,and normal distribution,regression analysis and other statistical methods were performed.Results All of the observed values were with normal distribution（P〉0.05）.In the six premature infants groups,the difference of the means of blood parameters are not significant between different genders（P〉0.05）,and the means and 95%CI were simultaneously calculated.Between different groups,except RBC（P〉0.05）,the other parameters were with significant differences（P〈0.01 or P〈0.05）.RBC,Hb,HCT,MCV,L%,N% and PLT were linearly correlated hours-age.Conclusion The blood parameters of premature infants in this study might be different with the data reported previously in other literatures.Comparing the parameters before and after 12 h,the changes could be more obvious.