《放射工作人员职业健康检查外周血淋巴细胞染色体畸变检测与评价》解读

Explanation of Test and Assessment of Chromosomal Aberrations on Occupational Health Examina- tions for Radiation Workers

《放射工作人员职业健康检查外周血淋巴细胞染色体畸变检测与评价》是为了规范放射工作人员体检项目外周血淋巴细胞染色体畸变的分析和结果评价而制订的。该文从目前国内开展此项工作的不同实验室间存在的诸如染色体畸变检测与结果评价不统一和现有国内外相关法律、法规和标准不完全适用于放射工作人员体检染色体畸变检测等问题，以及染色体畸变检测中染色体标本的制备方法、染色体畸变的分析鉴别方法、结果评价和影响染色体畸变检测质量的因素等方面，对该标准进行了较为全面的解读，为标准的贯彻实施和推广应用提供实验和理论依据。

Test and Assessment of Chromosomal Aberrations on Occupational Health Examinations for Radiation Workers was formulated for standardizing analysis and outcome assessment of chromosomal aberrations on occupational health examinations for radiation workers. In order to provide experimental and theoretical basis for implementation and extension of this standard, this paper interpreted the standaM com- prehensively, including some existed problems that methods on detection and outcome assessment of chromo- somal aberrations is not unified in different laboratories in China, and related criteria, laws and regulations at home and abroad are not fit for the detection of chromosomal aberrations for radiation workers very well; some introduction on methods of chromosomal slide preparation, discriminant analysis and outcome assessment of chromosomal aberration; and some influencing factors in the quality of chromosomal aberration detection.