宫颈癌的术后放化疗被引量：1

Postoperative radiotherapy and chemotherapy in cervical cancer

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摘要宫颈癌术后有高危因素患者易局部复发。已经证实有高危因素患者术后行辅助放疗能提高局部控制率，但不能提高总生存率。有研究显示同步放化疗较单纯放疗能提高生存率，但血液及消化系统不良反应较重。调强放疗（IMRT）能提高靶区适形度及剂量，同时降低周围正常组织剂量，IMRT有较好的局部控制率及生存率。 Local recurrence is more frequent in postoperative cervical cancer patients with high-risk factors. It is confirmed that adjuvant pelvic radiotherapy （RT） for the cervical cancer patients after surgery with high-risk factors can improve local control but can＇t improve the overall survival. Researches show that concur- rent chemo-radiotherapy （CCRT） can improve survival rates compared with radiotherapy, but the adverse effects such as leucopenia and gastrointestinal toxicity are observed frequently. Intensity-modulated radiation therapy （IMRT） has been developed to deliver a high radiation dose to an irregular target volume, with relative sparing of adjacent normal tissues. IMRT has excellent local tumor control and overall survival.

作者夏怡李云海赵森

机构地区复旦大学附属肿瘤医院闵行分院放疗科复旦大学附属肿瘤医院放疗科

出处《国际肿瘤学杂志》 CAS 2012年第8期622-625,共4页 Journal of International Oncology

关键词宫颈肿瘤放射疗法药物疗法 Uterine cervical neoplasms Radiotherapy Drug therapy

分类号 R737.33 [医药卫生—肿瘤]

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