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补肺颗粒治疗COPD稳定期临床研究 被引量:4

Clinical Research of Effects of Bufei Granule on Patients with Steady Chronic Obstructive Pulmonary Disease
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摘要 目的:评价补肺颗粒治疗慢性阻塞性肺疾病(COPD)稳定期的临床疗效。方法:将130例COPD稳定期患者随机分为两组,治疗组69例给补肺颗粒治疗,对照组61例给予安慰剂治疗,疗程均为30天。结果:治疗后总体疗效评价分治疗组明显好于对照组,可显著改善患者咳嗽、咯痰、喘促气短症状(P<0.05);治疗组较对照组呼吸困难程度减低(P<0.05)。结论:补肺颗粒为手段可以明显改善COPD稳定期患者临床症状,减轻呼吸困难程度。 Objective : To observe the effects of Bufei Granule on patients with steady chronic obstructive pulmonary dis- ease. Methods :130 cases were randomized into two groups : treatment group in which 69 cases were treated with Bufei Granule and control group in which 61 cases were treated with placebo. After 30 -day treatment, the patients'clinical symptoms were evaluated. Results : After 30 - day treatment, the respiratory symptom cough, expectoration and asthma were improved( P 〈 0.05 ). The dyspnea symptom in the treatment group were better than those in the control group ( P 〈 0. 05 ). Conclusion : Bufei Granule is quite effective in the improvement of clinical efficacy in COPD patients in stable phase.
出处 《中华中医药学刊》 CAS 2012年第8期1735-1737,共3页 Chinese Archives of Traditional Chinese Medicine
基金 国家自然科学基金资助项目(30672681) 天津市卫生局中医基金资助项目(2005007) 天津市卫生局科技基金项目(06KG07) 天津市科委应用基础及前沿技术研究计划基金资助项目(08JCZDJC15900)
关键词 COPD 稳定期 补肺颗粒 临床症状 COPD stable phase Bufei Granule pulmonary function clinical symptom
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参考文献3

  • 1慢性阻塞性肺疾病诊治指南(2007年修订版)[J].中华结核和呼吸杂志,2007,30(1):8-17. 被引量:8233
  • 2Cell BR , MacNee W. ATS/ERS Task Force, Stocndards, For the Diagnosig and Hreatment Patients with COPD:a Summary of the ATS/ERS Position paper[ J]. Eur Respir J ,2004,23:932 -946.
  • 3中华人民共和国卫生部制定发布.中药新药临床研究指导原则(试行)[S].北京:中国医药科技出版社,2002.

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