生物降解聚合物药物微球的制备方法

Preparation Methods of Biodegradable Polymeric Microspheres

综述了近年来生物降解聚合物药物微球的制备方法。随着药剂学的不断发展,传统的载药体系已经不能满足其需求。因此出现了许多新型的具有不同功能特性的药物载体。生物降解聚合物微球由于其结构组成可设计,并具有良好的安全性、生物相容性和生物降解性,可用作药物控释载体、表面改性、支架材料等,在生物医学领域获得了广泛的重视和应用。

Recent progress of preparation methods of biodegradable polymeric microspheres was reviewed. With the development of biophannaeeutieals, the traditional drug delivery systems had several inherent problems. So many new and advanced drug deliverys with different functions occurred. The biodegradable polymeric microspheres presen- ted perfect safety, biocompatibility and biodegradation and played an important role in the slow/controlled release drug and therapy in the field of clinical medicine, and had attractive application prospects.