遗传性精神发育迟滞的三级干预

Three Levels of Intervention to Inherited Mental Retardation

精神发育迟滞(MR)是指患儿智力能力显著低于正常,对社会环境适应能力明显减低的一组疾病,其病因多达数百种,遗传因素在其发病中发挥重要作用。现对遗传性MR的产前及孕前遗传学诊断及咨询方法,智力低下患儿康复指导和综合训练措施进行综述,以期为减少遗传性MR出生率,提高此类患儿生活质量提供理论借鉴。

Mental retardation（MR） is a cluster of disorders, characterized by low intelligence and low adaptive behavior. Its causes are as many as hundreds,while genetic factors play an important role in the path- ogenesis. Here is to make a review on genetic counseling for mothers who had delivered inherited MR child, and select appropriate prenatal diagnostic methods for early screening of MR, and provide rehabilitative guid- ance and comprehensive training protocol for MR. It will be helpful for reducing the birth rate, increasing the survival rate and improving quality of life of inherited MR children.