85例不孕症患者子宫内膜活检病理分析

PATHOLOGICAL ANALYSIS OF ENDOMETRIUM OF 85 CASES INFERTILITY PATIENTS

目的:通过对85例不孕症患者子宫内膜组织行病理活检,探讨不孕症患者子宫内膜病理变化与不孕症的关系,为临床诊治提供依据。方法:85例不孕症患者诊断性刮宫病理切片行临床病理分析。结果:85例不孕症患者原发性不孕71例,继发性不孕14例4。5例(52.94%)患者子宫内膜腺体分泌性反应,其中,子宫内膜腺体分泌反应良好12例(14.12%1,2/85),分泌反应欠佳、不良及无分泌33例(38.82%,33/85);子宫内膜增生期反应30例(35.29%),增生不足7例(8.24%),单纯性子宫内膜增长过长2例(2.35%),子宫内膜炎1例(1.18%)。结论:不孕症子宫内膜表现为分泌反应欠佳、不良、无分泌及增生性反应多见,不孕症的主要病因为卵巢黄体功能不全、失调和卵巢无排卵。

Objective：To investigate the relationship between pathological changes of endometrium and infertility by pathological biopsy of endometrium of 85 cases infertility patients, and provide bases for clinical diagnosis and treatment Methods：The endometrium of 85 cases infertility patients gotten by diagnostic curettage were analyzed by pathological detection.Results：Among 85 infertility patients, 71 cases were primarily infertility, 14 cases were secondary infertility. The endomelrial glands of 45 cases （52.94%） presented secretory reaction： Among which, the secretory reaction of 12 （14.12%, 12/85） was well, 33 cases （38.82%, 33/85） was poor or no secretion. 30 cases （35.29%） were endometrial hyperplasia reaction; the endometrial hyperplasia of 7 cases （8.24%） was insufficient; 2 cases （2.35%） were simple endometrial hyperplasia; 1 case （1.18%） was endometritis.Conclusions：The main appearances of endometrium of infertility are poor or no secretory reaction and productive reaction; and the main causes of infertility are luteal phase defect, disturbance and anovulation.