我院儿科病区抗菌药物应用分析

Antibiotic Use in The Pediatric Patients of Our Hospital

目的:调查我院儿科病区抗菌药物使用情况,为临床抗菌药物的合理使用与管理提供依据。方法:抽取我院儿科2010年10—12月间住院患儿的病历560份,对其中使用抗菌药物治疗的病例进行统计分析。结果:我院儿科病区使用抗菌药物的比例偏高,应用最多的是头孢菌素类抗菌药物,其次是头霉素类及大环内酯类抗菌药物。用药频度(DDDs)排序前5位的抗菌药物为头孢唑肟、头孢甲肟、阿奇霉素、头孢美唑和头孢他定,抗菌药物使用存在不合理现象。结论:儿科应进一步加强对抗菌药物的管理,加强临床医生对抗菌药物知识的学习。

OBJECTIVE： To investigate the pediatric utilization of antibiotics in our hospital to provide references for rational use and management of antibiotics.METHODS： During Oct.-Dec.period of 2010,a total of 560 case files of the pediatric patients of our hospital who were treated with antibiotics were collected and analyzed statistically.RESULTS： The ratio of antibiotics was high in department of pediatrics.Among the antibiotics,cephalosporin was used most frequently,followed by cephamycins and macrolides.In terms of DDDs ranking,the top 5 antibiotics were ceftizoxime,cefmenoxime,azithromycin,cefmetazole and ceftazidime.The antibiotic use was somewhat irrational.CONCLUSION： The management of antibiotics in department of pediatrics should be enhanced and it is necessary to tighten clinicians’ learning on the knowledge regarding the use of antibiotics.