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胆管癌发病机制研究进展 被引量:6

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摘要 胆管癌为一种起源于胆管上皮细胞恶性转化的恶性肿瘤,这种具有侵袭性并且发生机制尚未明确的恶性肿瘤绝大多数不可治愈。患者明确诊断时往往已处于疾病晚期。因此明确胆管癌的分子机制对于发展新的防治策略具有非常重要的意义。此文从危险因素、遗传学和表观遗传学、细胞因子介导的信号通路等方面就胆管癌发病机制近年来的研究进展作一综述。
出处 《国际消化病杂志》 CAS 2012年第4期200-204,共5页 International Journal of Digestive Diseases
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