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丝裂原活化蛋白激酶途径与肝细胞癌研究进展

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摘要 肝细胞癌(HCC)是世界第五大常见肿瘤,也是肝脏最常见的恶性肿瘤。丝裂原活化蛋白激酶(MAPK)是一类广泛存在于细胞内的高度保守的丝氨酸和苏氨酸蛋白激酶,是细胞内重要的信号转导系统,参与细胞的生长、发育、分化和凋亡等一系列病理生理过程。它是目前研究的热点,参与了包括肝癌在内的多种肿瘤的发生发展过程。
出处 《国际消化病杂志》 CAS 2012年第4期205-207,211,共4页 International Journal of Digestive Diseases
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