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多西他赛联合卡培他滨治疗复发转移乳腺癌的近期疗效观察 被引量:3

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摘要 目的:探讨多西他赛联合卡培他滨治疗复发转移乳腺癌的近期疗效。方法:收治复发转移乳腺癌患者90例,所有患者均采用卡培他滨联合多西他赛/环磷酰胺治疗。结果:本组患者总有效率为57.5%,其中Ⅱ期有效率为62.5%,Ⅲ期有效率为54.2%,不同分期的化疗有效率比较无明显差异(P>0.05)。两组血液毒性与胃肠道反应对比无明显差异(P>0.05)。没有发生因化疗而引起严重肝、肾功能改变者。结论:化疗可缩小乳腺癌的原发肿瘤及淋巴结,而卡培他滨联合多西他赛/环磷酰胺治疗能提高治疗疗效,减少术后不良反应的发生,改善患者的生存质量。
作者 曾浩 李前
出处 《中国社区医师(医学专业)》 2012年第21期140-140,共1页
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  • 1姜丽娜,于世英,熊慧华,张孟贤.胸苷磷酸化酶在癌组织中表达的研究[J].中华肿瘤杂志,2004,26(5):297-299. 被引量:72
  • 2[1]FISHER B, SAFFET E A, RUDOCK C,et al. Effect of local or systemic treatment prior to primary tumour removal on the production and response to a serum growth stimulating factor in mice[J]. Cancer Res ,1989,49:2002
  • 3[2]GOLDMAN J H,COLDMAN A J. A mathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate[J].Cancer Treat Rep, 1979,63:1727
  • 4[3]KOSCIELNY S, TUBIANA M, LE M G,et al. Breast cancer: relationship between the size of the primary tumour and the probability of metastatic dissemination[J]. Br J Cancer ,1984, 49:709
  • 5[4]HAYWARD J L, CARBONE P P, HEUSON J C, et al. Assessment of response to therapy in advanced breast cancer[J]. Br J Cancer ,1997,35:292
  • 6[5]CAYRE A, CACHIN F, MAUBLANT J,et al.Single static view 99mTc-sestamibi scintimammography predicts response to neoadjuvant chemotherapy and is related to MDR expression[J]. Int J Oncol ,2002,20(5):1049
  • 7[6]VAN DER HAGE J A, VAN DER VELDER C J H, JUAIEN J P,et al. Preoperative chemotherapy in primary operable breast cancer:results from the european organization for research and treatment of cancer trial 10902[J]. J Clin Oncol ,2001,19(22):4224
  • 8[7]FISHER B,BRYANT J, WOLMARK N. Effect of preoperative chemotherapy on the outcome of women with operable breast cancer[J]. J Clin Oncol, 1998,16(8):2672
  • 9[8]MAMOUNAS E P. NSABP Protocol B-27. Preoperative doxorubicin plus cyclophosphamide followed by preoperative or postoperative docetaxel[J]. Oncology (Huntingt) ,1997,11(6 Suppl 6):37
  • 10[9]MAMOUNAS E P, FISHER B. Preoperative (Neoadjuvant) chemotherapy in patients with breast cancer[J]. Seminars in Oncol ,2001,28(4):389

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