剖宫产围术期预防性应用抗生素354例临床分析

目的:探讨潜在感染因素剖宫产产妇围术期预防性应用抗生素的用药方案。方法:收治行剖宫产分娩产妇354例,回顾性分析潜在感染因素剖宫产产妇围术期抗生素的不同用药方案。根据抗生素使用情况分为两组,观察组180例,剖宫产术中断脐后开始给药,术后继续使用2天;对照组174例,手术结束后开始给药,共5天。抗生素应用头孢呋辛钠,为静脉给药。比较两组产妇术后感染、术后病率、术后体温恢复正常的时间及住院天数。结果:两组在术后感染、术后病率方面差异无统计学意义(P>0.05),观察组术后体温恢复正常的时间、术后平均住院天数短于对照组,差异有统计学意义(P<0.05)。结论:对潜在感染因素的剖宫产,术中1次用药,术后预防性应用抗生素2天即能达到预防感染的目的,术后过长时间预防性使用抗生素并不增加预防术后感染的效果。

Objective: To explore the optimum scheme used antibiotics of potential infection risk cesarean puerperal perioperative prophylactic.Methods: 354 cases of pregnant women with puerpera of cesarean parturition in Department of Obstetrics in our hospital from June 2010 to December 2011,antibiotics different therapeutic schemes of potential infection risk cesarean puerpera perioperative were retrospectively analyzed.They were divided into two groups,180 cases of the observation group,after umbilical cord was cut began to medicine,and postoperative continue to use 2 d;174 cases of the control group,began to medicine after the operation,5 d in all.cefuroxime sodium as antibiotics were given intravenously,Postoperative infection,postoperative morbidity,postopera-tive temperature returned to normal time and hospitalization days of two groups were compared.Results: Postoperative temperature returned to normal time,postoperativehospitalization days there were no significant differences(P > 0.05).Postoperative infection and the postoperative morbidity of observation group was shorter than the control group,the differences were statistically significant(P < 0.05).Conclusion: High risk of infection puerpera intravenous antibiotics,use once Antibiotic in the operation,postoperative prophylactic application of antibiotics in 2 days to reach the purpose of preventing infection,after long ues of prophylactic antibiotics for prevention of postoperative infection dose not increase effect.