牛肝菌对小鼠免疫功能影响的实验研究

Effect of Bolete on Mice Immune Function

目的:探讨牛肝菌对小鼠免疫功能的影响。方法:将牛肝菌的水溶液和脂溶液分别灌胃小鼠10 d,检测小鼠免疫器官重量、巨噬细胞吞噬能力、T淋巴细胞增殖情况及细胞因子产生的情况。结果:牛肝菌脂溶组中小鼠的多数指标均高于水溶组;并且牛肝菌对雌性小鼠的免疫增强作用强于雄性小鼠。结论:牛肝菌有增强免疫功能及抗肿瘤的作用。

Objective： To observe the effect of bolete on immune function of mice. Methods： Intragastric administration of bolete in aqueous solution or in lipid solution into the mice for 10 days consecutively. Organ weight of thymus and spleen, phagocytic capacity of macrophage, proliferation of T lymphocyte and cytokines inducement were investigated. Results： Indexes of lipid solution group were higher compared with that of aqueous group. Bolete manifested obvious effect on immunologic enhancement of female mice compared with the male mice. Conclusion： Bolete could enhance immune function and show anti-tumor effect in mice.