摘要
辐射诱发肿瘤发生的机制是复杂的。从动物致癌实验研究、人类肿瘤流行病学研究以及体外细胞转化体系等多种途径得到了大量证据 ,尤其是当代分子生物学的发展使人们对辐射诱发肿瘤有更深程度的了解。本文从当今分子生物学研究的几个热点领域介绍其研究现状及其发展趋势。
出处
《国外医学（肿瘤学分册）》
北大核心
2000年第4期219-221,共3页
Foreign Medical Sciences (Cancer Section)
参考文献10
-
1Chiarugi V,Magnelli L,Cinelli M,et al. Cellular and Molecular Biology Research . 1995
-
2Yount GL,Haas Kogan DA,Vidair CA. Cancer Research . 1996
-
3Zhou PK,Sproston AR,Marples B,et al. Radiation Research . 1998
-
4McConville CM,Stankovic T,Byrd PJ,et al. The American Journal of Human Genetics . 1996
-
5Bronner CE,Baker SM,Morrison PT,et al. Nature . 1994
-
6Hei TK,Krauss RS,Liu SX,et al. Carcinogenesis . 1994
-
7Kasid U,Suy S,Dent P,et al. Nature . 1996
-
8Barlow C,Hirotsune S,Paylor R,et al. Cell . 1996
-
9Little JB. Radiation Research . 1994
-
10Schneider J,Presek P,Braun A,et al. British Journal of Cancer . 1999
同被引文献10
-
1Amundson SA, Bitterner M, Meltzer P, et al. Induction of gene express as a monitor of exposure to ionizing radiation [J]. Radiat Res, 2001, 156(5): 657-661.
-
2Fomace Jr AJ, Alamo IJ and Hollander MC. DNA damageinducible transcripts in mammalian cells[J]. Proc Natl Acad Sci USA, 1988,85: 8800-8804.
-
3Fomace AJ. Mammalian genes induced by radiation; activation of genes associated with growth control [J]. Ann Rev Genet, 1992, 26: 507-526.
-
4Amundson SA, Myers TG and Fornace AJ. Roles for p53 in growth arrest and apoptosis: Putting on the brakes after genotoxic stress [J]. Oncogene, 1998, 17: 3287-3300.
-
5Amundson SA, Bittner M, Chen YD, et al. cDNA microarray hybridization reveals complexity and heterogeneity of cellul ar genotoxic stress responses[J]. Oncogene, 1999, 18: 3666-3672.
-
6Amundson SA, Shahab S, Bittner M, et al. Identincation of potential mRNA markers in peripheral blood lymphocytes for human exposure to ionizing radiation [J]. Radiat Res, 2000, 154: 342-346.
-
7Venter JC, Adams MD, Myers EW, et al. The sequence of the human genome[J]. Science, 2001, 291: 1304-1351.
-
8Koch PCA, Momenan R, Amundson SA, et al. Estimation of relative mRNA content by filter hybridization to a polvuridylic probe[J]. Biotechniques, 2000, 29: 712-714.
-
9Scherf L, Ross DT, Waltham M, et al. A gene expression database for the molecular pharmacology of cancer [J]. Genet, 2000, 24: 236-244.
-
10Tusher VG, Tibshiranni R and Chu G. Significant analysis of microarrys applied to the ionizing radiation response [J]. PNAS, 2001, 98(9): 5116-5121.
-
1黄正接,罗琪.肿瘤血管的分子靶向治疗[J].国际外科学杂志,2009,36(10):696-699.
-
2许宇彪,杨建荣.microRNA在人类恶性肿瘤中的研究进展[J].中国临床新医学,2016,9(9):833-837. 被引量：6
-
3史春梦,罗成基.P53及其家族的研究现状[J].科学,1999(9):56-57.
-
4黄灵潇,姚文秀.Her-2基因与乳腺癌靶向治疗[J].国际肿瘤学杂志,2014,41(10):760-763. 被引量：1
-
5黄吉武,McCormickJJ.以人类成纤维细胞体外转化体系为模型研究致癌多步骤机制[J].癌变．畸变．突变,1995,7(4):202-202.
-
6黄红洁,吴帮林,张娜娜,杨程.恶性肿瘤脑转移的神经外科治疗进展[J].武警后勤学院学报（医学版）,2016,25(8):694-696.
-
7郑传铭(综述),葛明华(审校).抑癌基因甲基化与涎腺腺样囊性癌[J].国际肿瘤学杂志,2010,37(9):676-679. 被引量：1
-
8王朝敏,徐道亮,张西志,张先稳.结直肠癌患者细胞质胸苷激酶的临床研究[J].山西医药杂志,2014,43(11):1295-1296. 被引量：1
-
9王泽朋,郑艺.浅谈化疗药物的耐药性[J].抗癌之窗,2016,0(4):53-56.
-
10徐从高.白血病多药耐药现象及其对策[J].国外医学（肿瘤学分册）,1995,22(5):299-300. 被引量：6
