乳腺癌卵巢转移17例报告

Report of 17 Patients with Ovary Metastases from Breast Cancer

目的 探讨有卵巢转移的乳腺癌患者的临床病程特点。方法 回顾性分析 195 8年～ 1990年 17例患者的临床资料。结果 从开始治疗原发肿瘤到卵巢转移确诊的中位生存期为 17个月 ;卵巢转移确诊后中位生存期为 16个月 ;1、3、5年的生存率分别为 68.8%、2 3 .0 %和 5 .9%。原发肿瘤诊断时的年龄、腋淋巴结状态、无瘤生存时间的长短及是否同时有卵巢外其他部位的转移等因素均影响患者的预后。结论 有卵巢转移的乳腺癌患者的预后很差 ,综合治疗可能是其最佳的治疗方法。

Objective To explore the clinical characteristics,treatment and prognostic factors of breast cancer patients with ovary metastases.Methods Clinical data of 17 cases between 1958～1990 were reviewed retrospectively.Results The median time from initial treatment of primary tumor to ovary metastases was 17 months,the median survival time after ovary metastases was 16 months.The 1 ,3 and 5 year survival rate was 68.8%,23.0% and 5.95%,respectively.The age and axillary nodal status at diagnosis of the primary tumor,the length of disease free interval,ovary metastases with concomitant involvement of extra ovary may provide information for predicting survival.Conclusion The prognosis of ovary metastases from breast cancer is rather poor.Multimodality treatment seems to be a better choice of approach.