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1,1-二取代-1,2-丙二烯化合物的合成

Synthesis of 1,1-Disubstituted-1,2-Propadiene
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摘要 以炔烃为原料,经磺酸炔丙酯与格氏试剂的SN2’反应合成1,1-二取代-1,2-丙二烯型化合物.该方法具有原料简单易得、反应条件温和、副反应较少、产率高等优点.产物经1 H NMR、13 C NMR、IR以及MS确证. The 1,1-disubstituted-1,2-propadiene was synthesized via SN2＇ reaction of Grignard reagent with sulfonic propargyl ester using alkyne as the raw material. The method has the advantages of readily available raw materials, mild conditions, few side reaction, high yields, et al. All products were verified by 1H NMR, 13C NMR, IR and MS.
作者 胡麟峰 王萍 章彦婧 洪雅 陈聪 毛国梁 郑卫新
机构地区 杭州师范大学材料与化学化工学院 东北石油大学化学化工学院
出处 《杭州师范大学学报（自然科学版）》 CAS 2012年第4期346-351,共6页 Journal of Hangzhou Normal University(Natural Science Edition)
基金 国家自然科学基金项目(20972037) 浙江省重点科技创新团队建设项目(2010R50017) 杭州师范大学优秀中青年教师支持计划项目(HNUEYT 2011-01-013) 黑龙江省留学归国人员科学基金项目(41417837-8-08016) 黑龙江省教育厅海外学人科研资助项目(1154H14)
关键词 1 1-二取代-1 2-丙二烯 磺酸炔丙酯 格氏试剂 SN2’反应 合成 1, 1-disubstituted-1,2-propadiene sulfonic propargyl ester Grignard reagent SN2＇ reaction synthesis
分类号 O627 [理学—有机化学]
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参考文献25

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共引文献1

杭州师范大学学报（自然科学版）
2012年 第4期

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