鼻咽癌首程γ-刀治疗9例报告分析

Some Views about the γ-knife as the First treatment in the Nasopharyngeal Carcinoma with 9 cases reports

目的 分析鼻咽癌首程 刀治疗的利弊。方法 1995年 7月至 1998年 10月我科收治了 9例鼻咽癌首程 刀治疗后的患者 ,原发灶中心剂量 4 0～ 50Gy ,边缘剂量 18～ 2 5Gy ,疗后 1周内来我科补充颈部外照射。颈部淋巴结阳性者照射 6 0～ 70Gy ,阴性者照射 4 5～ 50Gy。结果 4例在1～ 2年内原发灶复发 (占 4 4 4 % ) ,再作放疗后 2例存活 ,2例死亡。现存活 7例中 ,1例 3年后骨转移 ,正在接受治疗。结论 鼻咽癌首程 刀治疗后短期内原发灶复发率较高 ,疗效不优于常规放疗。

Objective To analyse the advantages and disadvantages of the  knife as the first treatment in the nasopharyngeal carcinoma.Methods From July 1995 to Oct.1998,9 patients with nasopharyngeal carcinoma firstly given  knife were treated in our department,the central dose wer 40—50Gy,and the bound dose were 18—25Gy,One week later,the patients were given neck irradiation.60—70Gy were given in positive neck and 45—50Gy were given in negative neck patients.Results 4 patients were recurred in 2 years,the second irradiation to the primary site was given,two patients were survival and two were dead.In the survival 7cases,one patient developed with bone metastases in the third year.Conclusion The patients with nasopharyngeal carcinoma firstly given  knife have a high local recurrence rate in short time,and their effects are not superior to the routine radiotherapy.