面神经神经失用的实验与临床研究

The study of facial neurapraxia

目的 :探讨面神经神经失用的临床特点和产生机制。方法 :制作面神经失用模型 ,测试诱发肌电位反应阈值 ,通过透射电镜观察面神经纤维的改变 ;采用神经兴奋性测试法和面瘫程度判定法对面瘫患者进行测试。结果 :实验模型的诱发肌电位的反应阈值平均需要 5 2 .5 min恢复到实验前水平 ,电镜观察到面神经髓鞘板层间开离 ;面神经失用患者均判断为失神经支配阴性 ,残留面肌功能 65 %以上。结论 :面神经失用是可逆性轻度面瘫 。

Objective:To study the clinical characteristics and mechanism of facial neurapraxia.Method:Patients were tested with nerve excitability method and judged the degree of facial paralysis. Animal mode of neurapraxia was made and threshold of evoked electromyographic potential was tested. The fibers of facial nerve were observed under transmission electromicroscope.Result:Average restoration time of evoked electromyographic potential was 52.5 min.The lamellar separation of myelin sheath of facial nerve was found under electromicroscope. Patients with facial neurapraxia was judged as denervation negative and residual function of facial muscles was above 65%.Conclusion:Facial neurapraxia is mild reversible facial paralysis and relevant to the lamellar separation.