期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

扩张型心肌病患者血清氨基末端脑钠肽与C反应蛋白相关性研究 被引量：3

Relationship between serum N-terminal pro-brain natriuretic peptide and CRP in dilated cardiomyopathy
下载PDF
导出
摘要 目的观察扩张型心肌病(DCM)患者血清氨基末端脑钠肽(NT-proBNP)与C反应蛋白(CRP)的相关性。方法选择2009年6月至2010年5月在该科住院的DCM患者32例,观察NT-proBNP与CRP、心功能、射血分数等的相关性。结果 NT-proBNP与CRP(P=0.003)、心功能(P=0.022)显著相关,NT-proBNP与射血分数(P=0.141)、CRP与射血分数(P=0.059)无显著相关性。结论 NT-proBNP与心力衰竭严重程度有关,并可能提示患者预后。 Objective To investigate the relationship between serum N-terminal pro-brain natriuretic peptide（NT-proBNP） and C-reactive protein（CRP） in the patients with dilated cardiomyopathy（DCM）.Methods 32 inpatients with DCM in this department from June 2009 to May 2010 were selected.The relationship between NT-proBNP with CRP,the heart function and left ventricular ejection fraction（LVEF） were observed.Results There was significant relationship between serum NT-proBNP with CRP（P=0.003） and heart function（P=0.022）.There was no significant correlation between NT-proBNP with LVEF（P=0.141） and CRP（P=0.059）.Conclusion NT-proBNP is related with the severity of heart failure and could imply the prognosis.
作者 陈远刚 何丹
机构地区 四川省都江堰市人民医院内科
出处 《重庆医学》 CAS CSCD 北大核心 2012年第25期2595-2596,2599,共3页 Chongqing medicine
关键词 心肌病 扩张型 利钠肽 脑 C反应蛋白质 cardiomyopathy,dilated natriuretic peptide,brain C-reactive protein
分类号 R542.2 [医药卫生—心血管疾病]
  • 相关文献

参考文献15

  • 1Sudoh T ,Minamino N ,Kangawa K ,et al. Brain natriuretic peptide-32: N-terminal six amino acid extended form of brain natriuretic peptide identified in porcine brain [J]. Biochem Biophys Res Commun, 1988,155 ( 2 ) : 726-732.
  • 2Balion C, Santaguida PL, Hill S, et al. Testing for BNP and NT-proBNP in the diagnosis and prognosis of heart fail ure[J]. Evid Rep Technol Assess(Full Rep) ,2006 (142) : 1-147.
  • 3Serge M, Roberto L, Inder S. Direct comparison of B2 type natriuretic peptide(BNP) and amino-terminal proBNP in a large population of patients with chronic and symptomatic heart failure:the valsartan heart failure(Val-HeFT) data [J]. Clin Chem,2006,52(8) :1528-1538.
  • 4Maisel AS, Krishnaswamy P, Nowak RM, et ah Rapid meas urement of Prtype natriuretic peptide in the emergency di agnosis of heart failure[J]. N Engl J Med,2002,347(3): 161-167.
  • 5赵雪燕,杨跃进,张健,党爱民,倪新海,黄洁,康晟,马卫华,赵冬云.B型利钠肽在诊断左心衰竭中的价值[J].中华医学杂志,2006,86(17):1165-1169. 被引量：97
  • 6Jourdain P,Jondeau G, Funek F, et al. Plasma brain atri uretie peptide-guided therapy to improve outcome in heart failure: the STARS-BNP muhieenter tudy[J]. J Am Coll Cardiol,2007,49(16) :1733-1739.
  • 7Shah MR. The STARBITE Trial :a randomized, pilot study of B-type natriuretic peptide-guided therapy in patients with advanced heart failure[J]. J Card Fail, 2011, 17(8) :613- 621.
  • 8Lainchbury JG, Troughton RW, Strangman KM, et al. N- terminal pro B-type natriuretic peptide guided treatment for hronic heart failure: results from the BATTLES- CARRED(NT-proBNP-assisted Treatment to lessen seri- al cardiac readmissions and death) trial[J]. J Am Coll Cardiol,2009,55(1) :53-60.
  • 9Maisel AS, Koon J, Krishnaswamy P, et al. Utility of B-natriuretic peptide as a rapid, point-of-care test for screen ing patients undergoing echocardiography to determine left ventricular dysfunction [J]. Am Heart J,2001,141 (3) :367-374.
  • 10Ferreira S, Almeida R, Guerrero H, et al. Prognosis of decom- pensated heart failure: role of NT-proBNP[J]. Rev Port Cardiol, 2007,26 ( 5 ) : 535-545.

二级参考文献15

  • 1Sudoh T, Kangawa K, Minamino N, et al. A new natriuretic peptide in porcine brain. Nature, 1988, 332:78-81.
  • 2Mukoyama M, Nakao K, Saito Y, et al. Increased huan brain natriuretic peptide in congestive heart failure. N Engl J Med, 1990,323:757-758.
  • 3Morrison KL,Harrison A,Krishnaswany P,et al. Vtility of a rapid B-natriuretic peptide (BNP) assay in differentiating CHF from lung disease in patients presenting with dyspnea. J Am Coll Cardiol,2002, 39:202-209.
  • 4Maisel AS, Koon J, Krishnaswamy P, et al. Utility of B-natriuretic poptide as a rapid, point-of-care test for screening patients undergoing echocardiography to determine left ventricular dysfunction. Am Heart J, 2001, 141:367-374.
  • 5Joung BY, Park BE, Kim DS, et al. B-type Natriuretic peptide predicts clinical presentations and ventricular overloading in patients with Heart Failure. Yonsei Medical J, 2003, 44:623-634.
  • 6Groenning BA, Nilsson JC, Sondergaavd L, et al. Evaluation of impaired left ventficular ejection fraction and increased dimensions by multiple neurohumoral plasma concentrations. European Journal of Heart Failure, 2001,3:699-708.
  • 7McDonagh TA, Robb SD, Murdoch DR, et al. Biochemical detection of left-ventricular systolic dysfunction. Lancet, 1998,351 :9-13.
  • 8Ry SD, Clerico A, Giannessi D, et al. Measurement of brain natriuretic peptide in plasma samples and cardiac tissue extracts by means of an immunoradiometric assay method. Scand J Clin Lab Invest, 2000, 60 : 81-90.
  • 9Fonseca C, Sarmento PM, Minez A ,et al. Comparative value of BNP and NT-proBNP in diagnosis of heart failure. Rev Port Cardiol,2004, 23:979-91.
  • 10de Bold A J, Bnmeau BG, de Bold MLK. Mechanical and neurocndocrine regulation of the endocrine heart. Cariovasc Res,1996, 31:7-18.

共引文献96

同被引文献40

  • 1刘越美,陈新宇.扩张性心肌病的发病机制和治疗进展[J].中医药导报,2005,11(4):76-77. 被引量：1
  • 2中华医学会心血管分会.中华心血管杂志编辑委员会,慢性心力衰竭诊断治疗指南.中华心血管杂志,2007,35(12):7-23.
  • 3Steudemann C, Bauersachs S, Weber K, et al. Detection and com- parison of microRNA expression in the serum of Doberman Pin- schers with dilated cardiomyopathy and healthy controls. BMC Vet Res,2013,9( 1 ) :12.
  • 4Alhomida AS. Effect of chronic renal hemodialysis on serum total, free and acyl carnitine concentrations in adult chronic pyelone- phritis patients. Arch Med Res, 1997,28 ( 1 ) : 101-107.
  • 5Lok BY, Dev M, Peter M, et al. Natriuretic peptides, respiratory disease, and the right heart. CHEST,2004,126 (4) : 1330-1336.
  • 6胡安义,梅尚文.心率震荡与慢性心力衰竭患者心功能N末端脑纳肽前体的关系.中华临床医学杂志(电子版),2011,5(7):2062-2065.
  • 7Groenning BA, Nilsson JC, Sondergaard L, et al. Evaluation of im- paired left ventricular ejection fraction and increased dimensions by multiple neurohumoral plasma concentrational. EJHF,2001,3 (6) :699.
  • 8Dourado VZ,Tanni SE, Vale SA, et al. Systemic manifestations in chronic obstructive pulmonary disease. J Bras Pneumol, 2006,32 (2) :161-171.
  • 9Hynninen KM, Breitve MH,Wiborg AB,et al. Psychological Char- acteristics of patients with chronic obstructive pulmonary disease. J Psychosom Res ,2005,9(9 ) :429-443.
  • 10朱元亮.脑钠肽在心力衰竭中的变化及诊断意义[J].中华心血管病杂志,2014,42(2):98-122.

引证文献3

二级引证文献18

重庆医学
2012年 第25期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部