亚甲蓝色素内镜对早期胃癌及癌前病变的诊断价值

Value of methylene blue chromoendoscopy in detection of early gastric cancer and precancerous lesions

目的探讨色素内镜对早期胃癌及癌前病变的诊断价值。方法将2010年1月至2011年12月该院消化内科门诊及住院患者194例,根据不同内镜检查分为实验组和对照组,104例行亚甲蓝色素内镜检查的为实验组,对照组90例行普通胃镜检查,比较亚甲蓝色素内镜和普通内镜的早期胃癌及癌前病变的检出率。结果实验组腺上皮肠化、不典型增生及腺癌检出率明显高于对照组(P<0.05);而腺上皮增生和腺瘤检出率两组比较,差异无统计学意义(P>0.05)。结论亚甲蓝色素内镜对早期胃癌及癌前病变的检出率更高,有助于早期胃癌及癌前病变的发现及诊断,具有方法简单、安全、实用的特点。

Objective To investigate the value of methylene blue chromoendoscopy in the detection of early gastric cancer and precancerous lesions.Methods 194 outpatients and inpatients in our hospital from January 2010 to December 2011 were divided into the experimental group and the control group according to different endoscopic examinations.The experimental group（104 cases） was performed the methylene blue chromoendoscopy and the control group（90 cases） received the conventional gastroscopic examination.The detection rates of early gastric cancer and precancerous lesion were compared between the two kinds of endoscopy.Results The detection rate of glandular epithelial intestinal metaplasia,atypical hyperplasia and adenocarcinoma in the experimental group was significantly higher than that in the control group（P〈0.05）.But the detection rate of glandular epithelial hyperplasia and adenoma had no statistical difference between the two groups（P〉0.05）.Conclusion The methylene blue chromoendoscopy has high detection rate for early gastric cancer and precancerous lesion and is conducive to find and diagnose early gastric cancer and precancerous lesion with the advantages of simple method,safety and practicability.