磷修饰金纳米粒子对葡萄糖氧化的电催化性能

Synthesis of phosphorus modified gold nanoparticles and their electrocatalytic activity for glucose oxidation

采用白磷还原法制备了磷修饰的金纳米粒子(Au-PNPs),Au-PNPs的粒径能够通过改变氯金酸与白磷的投料摩尔比进行有效调控.采用X-射线粉末衍射光谱(XRD)、傅里叶变换红外光谱(FT-IR)和透射电子显微镜(TEM)和电化学测试来表征Au-PNPs的形貌、结构和表面组成.循环伏安测试表明,在pH7.4的磷酸缓冲溶液中,Au-PNPs修饰电极对葡萄糖电化学氧化有良好的催化性能.通过与柠檬酸钠还原法制得的金纳米粒子(Au-CitNPs)的电化学性质比较,发现Au-PNPs对葡萄糖的电催化氧化具有优良的稳定性.基于此Au-PNPs修饰电极的葡萄糖无酶电化学传感器对于葡萄糖检测具有宽的线性检测范围(9.0×10-6～1.8×10-2mol/L)和低的检出限(5.0×10-6mol/L).

A simple one-step method is used to synthesize phosphorus modified gold nanoparticles （Au-P NPs） by using white phosphorus as reducing agent. The particle size of Au-P NPs can be easily controlled by varying the molar ratio of HAuCl4 to P4. The methodology, structure and surface composition of as-papered Au-P NPs are detailedly investigated by X-ray powder diffraction （XRD）, Fourier transform infrared （FT-IR） and transmission electron microscopy （TEM） measurements. Cyclic voltammetry measurements are applied to investigate the electrocatalytic performance of Au-P NPs for glucose oxidation. The electrochemical measurements show that Au-P NPs have higher electrocatalytic performance for glucose oxidation in pH 7.4 phosphate buffer solution （PBS） than the other Au NPs. Furthermore, the Au-P NPs modified electrode exhibits remarkably excellent electrochemical stability for electrooxidation of glucose. Thus, a sensitive enzyme-flee electrochemical sensor with wide linear range （9.0×10^-6 -1.8×10^-2 mol/L） and low detection limit （5.0× 10^-6 mol/L） can be easily developed for the detection of glucose in pH 7.4 phosphate buffer solution.