高渗盐水加α-糜蛋白酶雾化吸入促进排痰

A Study on Sputum Induction by Inhaled Atomized Hypertonic Saline and α-chymotrypsin

为探讨干咳患者促进排痰的方法 ,用 5 %氯化钠溶液 2 0 ml加 α-糜蛋白酶 40 0 0 U雾化吸入与单纯 5 %氯化钠溶液 2 0 ml雾化吸入作比较。结果 :前者有效率为 82 .5 % (33/ 40 ) ,后者为 42 .5 % (17/ 40 ) ,两者比较 ,差异有非常显著性 (P<0 .0 1)。提示 :雾化吸入高渗盐水加 α 糜蛋白酶可明显提高干咳患者痰标本采集的成功率。该方法简单、实用 。

To explore the method for inducing sputum from dry cough patients, two groups of patients were studied. One group inhaled 20 ml of 5% atomized sodium chloride solution and 4 000 U of α chymotrypsin, the other inhaled only 20 ml of 5% sodium chloride solution. The effective rate was 82 5% (33/40) in the former group and 42 5% (17/40) in the later ( P <0 01). It was suggested that combined use of inhaled atomized hypertonic saline and α chymotrypsin could increase the successful rate of sputum induction from the patients with dry cough. This method was simple and practical.