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共激活因子PGC-1α的研究进展 被引量:5

Research Advance of Coregulator PGC-1α
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摘要 共调节因子通过与特定转录因子结合进而调节下游靶基因的表达。该文综述了共激活因子PGC-1α的分子结构特征及表达模式,介绍了该因子在适应性产热、线粒体生物合成、肌肉类型转换、肝脏糖异生和脂肪酸氧化等生理调控方面的研究进展。 The targeted genes are regulated by a set of proteins that docking transcription factors called transcription coregulators. This paper reviewed the structure of PGC-1α,its expression pattern, and physiology taboli regulation on adaptive thermogenesis,mitochondria biogenesis, muscle fiber conversion,glucose me sm and fatty acid oxidative.
出处 《中国牛业科学》 2012年第4期35-38,共4页 China Cattle Science
基金 国家农业部现代肉牛产业技术体系专项(No.CARS-38) 国家自然科学基金(No.30972080) 陕西省农业科技创新项目(No.2012NKC01-13)资助
关键词 PGC-1Α 共激活因子 代谢调控 PGC-1α coregulator metabolism regulation
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参考文献32

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  • 4季宇彬,高鹏,邹翔.G2/M检验点调控机制研究概述[C].2008年中国药学会学术年会暨第八届中国药师周论文集,2008.
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