期刊文献+

替吉奥联合奥沙利铂治疗晚期胃癌的效果观察及护理 被引量:6

S-1 COMBINED WITH OXALIPLATIN IN THE TREATMENT OF ADVANCED GASTRIC CANCER
下载PDF
导出
摘要 目的探讨替吉奥联合奥沙利铂(SOX)治疗晚期胃癌的疗效及护理方法。方法对58例晚期胃癌患者采用SOX方案化疗,并进行心理及临床护理干预,评估临床疗效及护理的作用。结果 58例患者中总有效率为46.6%,疾病控制率70.7%,疾病进展时间5.7个月。结论 SOX治疗晚期胃癌的疗效可靠,良好的护理干预可提高药物疗效。 Objective To explore the curative effect of the combined use of S-1 and oxaliplatin(SOX) on advanced gastric cancer.Methods 58 patients with advanced gastric cancer were treated with SOX scheme.Psychological and clinical nursing interventions were implemented and the clinical efficacy and nursing roles were studied.Results In the 58 cases,the total effective rate was 46.6%,and the disease control rate was 70.7%.The disease progression lasted 5.7 months.Conclusion SOX is reliable in the treatment of advanced gastric cancer and good nursing intervention can improve the efficacy of drugs.
作者 韩洪冰
机构地区 临沂市肿瘤医院
出处 《山东医学高等专科学校学报》 2012年第3期205-206,共2页 Journal of Shandong Medical College
关键词 胃癌 替吉奥 奥沙利铂 护理 Gastric cancer S-1 Oxaliplatin Nursing
  • 相关文献

参考文献4

二级参考文献25

  • 1钱军,秦叔逵,梅静峰,陈映霞,邵志坚,何泽明.奥沙利铂联合卡培他滨二线治疗晚期胃癌的临床观察[J].中华肿瘤杂志,2004,26(12):746-748. 被引量:60
  • 2Andre T,Bensmaine M, Louvet C, et al. Multicenter phase Ⅱstudy of bimonthly high-dose leucovorin, fluorouracil infusion, and oxaliplatin for metastatic colorectal cancer resistant to the same leucovorin and fluorouracil regimen[J].J Clin Oncol, 1999,17:3560-3568.
  • 3Wilson RH, Lehky T, Thomas RR, et al.Acute oxaliplatin-induced peripheral nerve hyperexcitability[J].J Clin Oncol, 2002,20:1767-1774.
  • 4Lehky TJ, Leonard GD, Wilson RH, et al. Oxaliplatin-induced neurotoxicity: acute hyperexcitability and chronic neuropathy[J]. Muscle Nerve, 2004,29(3):387-392.
  • 5Grolleau F,Gamelin L, Boisdron-Celle M, et al.A possible explanation for a neurotoxic effect of the anticancer agent oxaliplatin on neuronal voltage-gated sodium channels[J]. J Neurophysiol, 2001,85:2293-2297.
  • 6Lersch C, Schmelz R, Eckel F, et al. Prevention of oxaliplatin-induced peripheral sensory neuropathy by carbamazepine in patients with advanced colorectal cancer[J]. Clin Colorectal Cancer, 2002,2:54-58.
  • 7Gamelin L,Boisdron-Celle M, Delva R, et al. Prevention of oxaliplatin-related neurotoxicity by calcium and magnesium infusions: a retrospective study of 161 patients receiving oxaliplatin combined with 5-Fluorouracil and leucovorin for advanced colorectal cancer[J].Clin Cancer Res, 2004,10(12 Pt 1):4055-4061.
  • 8Cascinu S,Catalano V,Cordella L, et al.Neuroprotective effect of reduced glutathione on oxaliplatin-based chemotherapy in advanced colorectal cancer. A randomized, double-blind, placebo-controlled trial[J]. J Clin Oncol,2002,20:3478-3483
  • 9Moiseyenko VM,Ajani JA,Tjulandin SA,et al.Final results of a randomized controlled phase Ⅲ trial (TAX 325) comparing docetaxel (T) combined with cisplatin (C) and 5-fluorouracil (F)to CF in patients (pts) with metastatic gastric adenocarcinoma (MGC)[ J ].J Clin Onc,Proc Am Soc Clin Oncol,2005,23:Abstract 4002.
  • 10Al-Batran S,Hartmann J,Probst S,et al.A randomized phase Ⅲ trial in patients with advanced adenocarcinoma of the stomach receiving first-line chemotherapy with fluorouracil,leucovorin and oxaliplatin (FLO) versus fluorouracil,leucovorin and cisplatin (FLP)[J].J Clin Onc,Proc Am Soc Clin Oncol,2006,24:Abstract 4016.

共引文献379

同被引文献35

引证文献6

二级引证文献47

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部