和胃安神方治疗原发性失眠的临床研究

Clinical study on people with primary insomnia treated by TCM of Harmonizing Stomach to Tranquilize

目的观察和胃安神方对原发性失眠的临床症状和睡眠质量的改善效果。方法将104例原发性失眠患者随机分为治疗组(52例)和对照组(52例),治疗组采用和胃安神方治疗,对照组采用艾司唑仑片治疗,疗程均为4周,治疗前后均用失眠中医证候量表、匹兹堡睡眠质量指数量表检测评分。结果治疗组临床疗效总有效率为96.2%,对照组总有效率为73.1%(P<0.01)。治疗组和对照组的睡眠质量完全改善率分别为86.5%和69.2%(P<0.05)。治疗后2组的PSQI总分分别为(8.12±2.48)分和(10.07±3.13)分(P<0.01)。结论和胃安神方治疗原发性失眠效果良好,能明显改善失眠者的临床症状和睡眠质量。

Objective To investigate the efficacy of the TCM decoction of harmonizing stomach to tranquilize for people with primary insomnia on clinical symptom and sleep quality. Methods 104 insomniacs were randomly divided into the trial group （52 cases） and the control group （52 cases） , the trial group was treated by TCM decoction of harmonizing stomach to tranquilize while the control group by estazolam. Both groups took 4 weeks for a period of treatment. Before and after treatment detect the clinical symptom and Pittsburg Sleep Quality Index （PSQI） values of all objects by Measuring Scale of TCM Syndrome for Insomnia （MSSI） and PSQI Scale respectively. Results The total effective rate on ameliorating clinical symptoms of the trial group was 96.2%, which of the control group was 73.1% （P〈 0. 01 ）. The improving rate of sleep quality of the trial group was 86.5%, which of the control group was 69.2% （P〈0.05）. After treatment the values of sleep quality were （8.12±2.48） and （10.07±3.13） （P〈0. 01 ） in the trial and control group respectively. Conclusion The TCM decoction of harmonizing stomach to Tranquilize has a significant effect to primary insomnia, remarkably improving the clinical symptoms and sleeping quality of the insomniacs.