妊娠合并慢性丙型病毒性肝炎患者胰岛素抵抗状况分析

Analysis of insulin resistance in pregnant patients with chronic hepatitis C

目的分析妊娠合并慢性丙型病毒性肝炎患者的胰岛素抵抗状况。方法选择87例妊娠合并慢性丙型病毒性肝炎患者为观察组，80例未合并丙型肝炎孕妇为对照组。检测并比较两组空腹血糖（FPG）、空腹胰岛素（FINS）水平和胰岛素抵抗指数（IRS）。结果观察组FPG、FINS、IRS分别为（5．40±1．01）mmol/L、（69．43±38．05）mU／L和（16．65±12．29），对照组分别为（4．53±0．56）mmoL／L、（50．54±20．07）mU／L和（10．17±4．66），两组差异均有统计学意义（t=3．26、3．87、4．01，均P〈0．05）。结论妊娠合并慢性丙型病毒性肝炎患者存在明显的胰岛素抵抗。

Objective To observe the insulin resistance in pregnant patients with chronic hepatitis C. Methods 87 pregnant patients with chronic hepatitis C were chosen as observation group,while 80 healthy pregnant women were chosen as control group. The fasting blood glucose （FPG）, fasting insulin （FINS） and insulin resistance index（IRS） were detected and compared in the two groups. Results The FPG,F[NS and IRS of the observation group were （ 5.40 ± 1.01 ） mmol/L, （ 69.43 ± 38.05 ） mU/L and （ 16.65 ± 12.29 ）, respectively, which were significantly higher than those of the control group[ （4.53 ± 0.56 ） retool/L, （ 50.54 ± 20.07 ） mU/L and （ 10. 17 ± 4.66 ） ], respectively（ t = 3.26,3.87,4.01, all P 〈 0.05 ）. Conclusion There was significant insulin resistance in pregnant pa- tients with chronic hepatitis C.