期刊文献+

Asef蛋白在肿瘤发生中的作用

The Role of Asef Protein in Carcinogenesis
原文传递
导出
摘要 Asef是可与APC基因的Arm结构相结合的两种蛋白之一,APC-Asef复合体参与细胞形态学、细胞迁移和神经元功能的调节作用,其与肿瘤的发生、发展、侵袭和转移密切相关。全文就Asef蛋白在肿瘤中的作用作一综述。
出处 《肿瘤学杂志》 CAS 2012年第7期549-552,共4页 Journal of Chinese Oncology
基金 湖北省卫生厅科研基金(JXZB76)
  • 相关文献

参考文献1

二级参考文献34

  • 1Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996; 87:159-170.
  • 2Rustgi AK. The genetics of hereditary colon cancer. Genes Dev 2007; 21:2525-2538.
  • 3Hirschl D, Bayer P, Muller O. Secondary structure of an ar- madillo single repeat from the APC protein. FEBS Lett 1996; 383:31-36.
  • 4Graham TA, Weaver C, Mao F, Kimelman D, Xu W. Crystal structure of a beta-catenin/Tcf complex. Cell 2000; 103:885- 896.
  • 5Ha NC, Tonozuka T, Stamos JL, Choi HJ, Weis WI. Mecha- nism of phosphorylation-dependent binding of APC to beta- catenin and its role in beta-catenin degradation. Mol Cell 2004; 15:511-521.
  • 6Huber AH, Weis WI. The structure of the beta-catenin/E- cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin. Cell 2001 ; 105:391-402.
  • 7Sampietro J, Dahlberg CL, Cho US, Hinds TR, Kimelman D, Xu W. Crystal structure of a beta-catenirdBcl9/Tcf4 complex. Mol Cell 2006; 24:293-300.
  • 8Xing Y, Clements WK, Kimelman D, Xu W. Crystal structure of a beta-catenirdaxin complex suggests a mechanism for the beta-catenin destruction complex. Genes Dev 2003; 17:2753- 2764.
  • 9Xing Y, Clements WK, Le Trong I, et al. Crystal structure of a beta-catenin/APC complex reveals a critical role for APC phosphorylation in APC function. Mol Cell 2004; 15:523-533.
  • 10Xu W, Kimelman D. Mechanistic insights from structural studies of beta-catenin and its binding partners. J Cell Sci 2007; 120:3337-3344.

共引文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部